Desensitisation to aspirin in antiphospholipid antibody syndrome.

cases. Patch testing with a battery of sunscreens gave a positive reading (++) at 48 and 96 h to butyl methoxydibenzoylmethane 2% (Parsol 1789) in both cases (Fig. 1). Since only one of the sunscreens contained parsol, we decided to test with other sunscreens. The results are shown in Table 1. All sunscreens that gave a positive patch test reaction contained octocrylene, which is included in some sunscreen series only. In order to confirm the positivity of octocrylene, we requested this component from the laboratory Chemotechnique for patch testing. Readings were positive (+++) in both cases at 48 and 96 h. Of the sunscreens tested, the only one with a negative result was the physical sunscreen Eucerin Kids Sun Micropigment Lotion, which has no chemical components. We report two cases of allergic contact dermatitis in infants who were sensitised to sunscreen (Parsol 1789 and octocrylene). Although these compounds have traditionally been considered safe, reports of allergic reactions are increasingly frequent. Octocrylene is an emergent allergen, which appears to cause direct allergic contact dermatitis in children, and allergic photocontact dermatitis in adults, often in patients previously diagnosed with photocontact allergy to topical ketoprofen. Therefore, we recommend patch testing with a comprehensive series of sunscreen ingredients, as well as with the actual commercially available sunscreens responsible for patient dermatitis, and awareness of the risk of applying chemical filters in infants. Only physical sunscreen should be used in this age group.